Source 20240722_182606

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Direct transcription20240722_182606
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Page labelPage 394 of 399
Navigation pathPipeline of GD & GBA-PD > Supplement > Assay Truncation > Structure of aSyn > Synapse and aSyn > TM for aSyn programs
SectionGBA-PD, GD, and α-Synuclein Pipeline
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Headings

  • Three major αsyn domains (N-terminal / NAC / C-terminal acidic tail), Synapse and aSyn (Calleri 2015 90% presynaptic deposits), TM for aSyn programs (Monomer / Pansson 2018 fibril CDMS, αSyn oligomer enrichment plan, paSyn / Fragments / LB / PD vs MSA / DLB SPAL? rows)
  • Three major αsyn domains
  • Synapse and aSyn
  • TM (target modulation) for aSyn programs
  • PD vs MSA / DLB ? (SPAL?)

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