Source 20240722_182447

Canonical Links

item	link
Direct transcription	20240722_182447
Raw photo	data/raw/photos/20240722_182447.jpg

Source Metadata

field	value
Page label	Page 340 of 345
Navigation path	Pipeline of GD & GBA-PD > Supplement > Antibody > Epitope mapping > APOE > AQP4 potentiator
Section	GBA-PD, GD, and α-Synuclein Pipeline
Uncertain spans	0
Embedded images	0
Related photos	2

Headings

• AQP4 potentiator (mislocalization / amyloid / p-tau), Glymphatic system in PD, AQP4 SNP, Burfeind 2017 cohort, Target validation, Ariba procurement, Astrocyte start
• AQP4 potentiator
• Increased amyloid accumulation in AQP4 KO × APP-PS1 mice (Mol Neurodegener. 2015, 10:58)
• Exacerbation of p-tau accumulation and neuronal death in AQP4 KO × PS19 mice
• Glymphatic system in PD
• SNP
• Questions
• Target validation
• IBA / Ariba US
• Astrocyte

Related Source Notes

• 20240722_182443 - overlaps_upper_apoe_apoe4_block
• 20240722_182451 - continues_lower_astrocyte_block

Wiki Coverage

• Section: GBA-PD, GD, and α-Synuclein Pipeline
• Catalog: Source Catalog
• Navigation: Navigation Path Index

Topic-level synthesis should link back to this source note or directly to the canonical transcription when making specific claims.